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The centenary of insulin

2021, Frederick G. It is the 100th anniversary of the discovery of insulin by Bunting and Charles Best, the greatest discovery in the history of world medicine.

In May 1921, experiments began in Toronto, Canada, culminating in the synthesis of commercially available insulin. Frederick Bunting and Charles Best conducted experiments on dogs with diabetes, with limited success. The achievement came when one of the dogs, named by the Toronto team Marjorie, survived 70 days by injections of pancreatic extract or "isletin," as the team called it. On January 23 of the following year, a person with diabetes underwent the first successful insulin injection.

There were other important developments in the chronology of the discovery of insulin that prompted us from the original idea, which led to the study of mass production and widespread distribution of insulin beyond North America. Of course, working in Toronto in the late 1920s and early 1921s did not occur in a vacuum. The International Diabetes Federation will use the opportunity to mark many relevant dates and topics in the history of diabetes, including pioneering work discovered before and after events that have transformed diabetes care over the past 100 years.

While these historic events have saved and improved the lives of millions of people with diabetes, it is important to remind yourself that insulin and other diabetes treatments and care are still beyond the reach of many who need it.

Providing universal access to insulin remains a global challenge for all those who request it. Barriers to access and access are numerous and complex, reflecting the many steps involved in the production, distribution and pricing process, as well as the infrastructure needed to ensure the proper and safe use of insulin.

The united, global diabetes community has a significant number, influence and decision to make significant changes. We must take up the challenge. We owe it to millions of families affected by diabetes and owe it to us to inherit Banting and Best. Together, we must address the acute question on the lips of many people who may not be able to ask themselves this question: "How much longer?"

Insulin for 100 years: a life-saving discovery, but much remains to be done

• Journey to a medical miracle

October 1920 - Frederick J. Banting has an idea for insulin research

November 1920 - Bunting meets John J.R. McLeod

May 1921 - Bunting begins experiments assisted by Charles Best

August 1921 - First used to regulate blood glucose in dogs with severe diabetes.

Insulin taken

o December 1921 - James B.. Colip joined a scientific team to purify raw insulin extract

January 1922 - Leonard Thompson receives his first successful insulin injection on January 23

October 1923 - Bunting and McLeod are awarded the Nobel Prize for Insulin

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